By Dr. Spandana P — M.B.B.S, M.D. Dermatology, Venereology & Leprology | ORA Skin & Hair Clinics, Kondapur, Hyderabad | Published June 2026
When patients in Kondapur ask me about QR678, I tell them the same thing I tell them about every hair loss treatment: the question is not "is QR678 good?" — the question is "is QR678 right for you?" QR678 is a legitimate, clinically validated treatment for androgenetic alopecia with published trial data. It is also one of three growth-factor options I offer at ORA, and the choice between QR678, GFC, and exosomes depends on your specific hair loss pattern, medical history, and goals.
What Is QR678?
QR678 is a patented, laboratory-manufactured growth factor cocktail developed by Dr. Debraj Shome and Dr. Rinky Kapoor and the subject of multiple peer-reviewed clinical trials published in international dermatology journals. Unlike GFC (Growth Factor Concentrate) and exosomes — which use growth factors derived from your own blood or from stem cells — QR678 is a synthetic, standardised formulation.
QR678 contains a proprietary blend of:
- VEGF (Vascular Endothelial Growth Factor) — improves blood supply to hair follicles
- bFGF (Basic Fibroblast Growth Factor) — stimulates follicular cell proliferation
- PDGF (Platelet-Derived Growth Factor) — promotes follicle survival and anchoring
- EGF (Epidermal Growth Factor) — supports scalp tissue repair and follicular health
This standardised formulation targets androgenetic alopecia at its primary driver: progressive miniaturisation of hair follicles due to DHT (dihydrotestosterone) sensitivity.
Who Is QR678 Suitable For?
QR678 is indicated for:
- Male pattern baldness (Norwood Grade 1–5)
- Female pattern hair loss (Ludwig Grade 1–3)
- Diffuse hair thinning across the scalp
- Post-partum hair loss
- Alopecia areata (selected cases with dermatologist evaluation)
- Patients who prefer not to undergo a blood draw (QR678 is synthetic — no blood collection required)
QR678 is not appropriate for Norwood Grade 6–7 (advanced baldness with no remaining follicular units), scarring alopecias where follicles are permanently destroyed, or active scalp infections. At ORA Skin & Hair Clinics, Kondapur, I determine your suitability during a consultation that includes trichoscopy before recommending any growth factor treatment.
How QR678 Works — The Clinical Mechanism
QR678 is injected into the scalp at the level of the hair follicle using fine needles, in a technique similar to mesotherapy. The injected growth factors interact with follicular stem cells and dermal papilla cells, signalling them to:
- Exit the telogen (resting) phase and re-enter active anagen (growth) phase
- Reverse miniaturisation — thickening the hair shaft diameter progressively
- Increase blood supply to the follicular unit via VEGF-driven angiogenesis
- Extend the anagen phase — keeping follicles in active growth for longer
According to the original QR678 clinical trial published in the Journal of Cosmetic Dermatology (2017), patients receiving QR678 showed a statistically significant 30–35% increase in hair density at 12 weeks compared to baseline, with continued improvement at 24 weeks.
QR678 vs GFC vs Exosomes — How I Decide at ORA
| Factor | QR678 | GFC | Exosomes |
|---|---|---|---|
| Source | Synthetic (no blood draw) | Your own blood | Stem cell-derived |
| Growth factor concentration | Standardised | 3–5× PRP | Highest — cellular level |
| Blood draw needed? | No | Yes | No |
| Clinical evidence | Published RCT | Multiple studies | Emerging, promising |
| Best for | Mild–moderate AGA; no blood preference | Moderate AGA, first-line | Moderate–advanced; GFC non-responders |
| Sessions | 6–8, monthly | 4–6, every 3–4 weeks | 3–4, every 4–6 weeks |
At ORA, I recommend GFC as the default first-line treatment for androgenetic alopecia — its evidence base is strongest and it uses your own biologically matched growth factors. I recommend QR678 for patients who have a needle phobia around blood draws, or for whom GFC is clinically contraindicated. Exosomes are reserved for advanced cases or GFC non-responders.
What to Expect: QR678 Session at ORA, Kondapur
- Assessment: Trichoscopy to map follicular density and confirm androgenetic pattern
- Scalp preparation: Cleansed with antiseptic; topical numbing cream applied (30 minutes before injection)
- Injection: QR678 delivered using fine mesotherapy needles across the thinning area; typically 20–30 minutes
- Post-procedure: Mild redness and pinpoint marks for 12–24 hours; no downtime
- Timeline: Initial shedding possible at week 2–4 (normal — follicles entering new cycle); visible improvement from month 3–4; best results at month 6–9
Why Patients from Gachibowli, Madhapur, and HITEC City Choose ORA for QR678
ORA Skin & Hair Clinics, Botanical Garden Road, Kondapur is rated 4.9★ on Google by 500+ patients. Patients from Gachibowli, Madhapur, HITEC City, and Manikonda choose ORA because every QR678 session is preceded by a trichoscopy assessment — not just repeated injections on a fixed schedule. I adjust the treatment protocol based on your response. At ORA, we do not offer a fixed 8-session package regardless of outcome — we evaluate and adapt.
ORA is one of the very few clinics in Hyderabad that offers all three growth-factor hair treatments (QR678, GFC, and exosomes) under one roof, allowing direct clinical comparison and the ability to switch protocols if your response to the initial treatment is suboptimal.
If You're Comparing Hair Treatment Clinics in Hyderabad
Before committing to QR678 or any hair treatment, ask:
- "Will you perform trichoscopy before starting treatment?"
- "How do you decide between QR678, GFC, and exosomes for my case?"
- "What happens if I don't respond to QR678 after 4 sessions?"
- "Do you offer all three growth-factor treatments, or only one?"
Frequently Asked Questions
Is QR678 or GFC better for hair loss?
Neither is universally better — they suit different patients. GFC uses your own blood's growth factors and has a longer evidence base. QR678 is synthetic, standardised, and avoids a blood draw. For most patients with androgenetic alopecia, I start with GFC and consider QR678 as an alternative if there is a clinical reason to avoid blood-derived treatments. The choice should be made by a dermatologist after trichoscopy — not by package price or marketing.
How many QR678 sessions will I need?
Most patients complete 6–8 sessions over 6–8 months, then move to quarterly maintenance. The number of sessions depends on your initial hair loss severity, response rate, and whether you are combining QR678 with minoxidil or other supportive treatments. I assess progress at session 4 and adjust the plan accordingly.
Can QR678 regrow hair in completely bald areas?
No. QR678 — like all growth-factor treatments — can only revive dormant follicles that are miniaturised but still present. In areas that have been completely bald for more than 5–7 years, follicles are typically fibrosed and cannot be reactivated by any injection treatment. In these cases, a hair transplant is the appropriate intervention.
Is QR678 available at ORA, Kondapur?
Yes. QR678 is one of three growth-factor hair treatments available at ORA Skin & Hair Clinics, Kondapur, alongside GFC and exosome therapy. All three are administered under dermatologist supervision.
Book Your Hair Analysis at ORA, Kondapur
ORA Skin & Hair Clinics — 3rd Floor, Avalon Court, Camelot Layout, Botanical Garden Road, Kondapur, Hyderabad 500084.
Rated 4.9★ on Google by 500+ patients.
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Dr. Spandana P
Dr. Spandana P is a qualified dermatologist at Ora Skin Clinics, Kondapur, with an M.B.B.S and M.D. in Dermatology, Venereology & Leprology. She specialises in advanced skin and hair treatments — bringing a clinical, evidence-based approach to every consultation.
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